Dietary Restriction on Hepatic Metabolism and Hepatotoxicity
نویسندگان
چکیده
Received May 8, 2007; revision accepted for publication June 18, 2007. Correspondence: Pei-Yu Wang, Department of Social Medicine and Health Education, School of Public Health, Peking University, Xueyuan Road 38, Haidian District, Beijing, 100083, China. e-mail: [email protected] One-Day Dietary Restriction Changes Hepatic Metabolism and Potentiates the Hepatotoxicity of Carbon Tetrachloride and Chloroform in Rats
منابع مشابه
Alterations in hepatic glucose and energy metabolism as a result of calorie and carbohydrate restriction.
UNLABELLED Carbohydrate restriction is a common weight-loss approach that modifies hepatic metabolism by increasing gluconeogenesis (GNG) and ketosis. Because little is known about the effect of carbohydrate restriction on the origin of gluconeogenic precursors (GNG from glycerol [GNG(glycerol)] and GNG from lactate/amino acids [GNG(phosphoenolpyruvate (PEP))]) or its consequence to hepatic ene...
متن کاملShort-term dietary phosphate restriction up-regulates ileal fibroblast growth factor 15 gene expression in mice
Members of the fibroblast growth factor (FGF) 19 subfamily, including FGF23, FGF15/19, and FGF21, have a role as endocrine factors which influence the metabolism of inorganic phosphate (Pi) and vitamin D, bile acid, and energy. It has been reported that dietary Pi regulates circulating FGF23. In this study, the short-term effects of dietary Pi restriction on the expression of FGF19 subfamily me...
متن کاملPhysiogenomic analysis of weight loss induced by dietary carbohydrate restriction
BACKGROUND Diets that restrict carbohydrate (CHO) have proven to be a successful dietary treatment of obesity for many people, but the degree of weight loss varies across individuals. The extent to which genetic factors associate with the magnitude of weight loss induced by CHO restriction is unknown. We examined associations among polymorphisms in candidate genes and weight loss in order to un...
متن کاملEffects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice.
BACKGROUND/AIMS We previously reported that acute betaine treatment induced significant changes in the hepatic glutathione and cysteine levels in mice and rats. The present study was aimed to determine the effects of dietary betaine on the metabolism of sulfur-containing amino acids. METHODS/RESULTS Male mice were supplemented with betaine (1%) in drinking water for up to 3 weeks. Changes in ...
متن کاملActivation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats
Triptolide (TP), a diterpenoid isolated from Tripterygium wilfordii Hook F, has an excellent pharmacological profile of immunosuppression and anti-tumor activities, but its clinical applications are severely restricted due to its severe and cumulative toxicities. The farnesoid X receptor (FXR) is the master bile acid nuclear receptor and plays an important role in maintaining hepatic metabolism...
متن کامل